Sites and allele Frequencies GRCh38 (v20210103)
The VCF is annotated with rsIDs from dbSNP151, and the following INFO fields:
| AC: | Allele count in called genotypes in WBBC |
| AF: | Allele frequency in called genotypes in WBBC |
| AN: | Total number of alleles in called genotypes in WBBC |
| NS: | Total number of samples in called genotypes in WBBC |
| North_AF: | Allele frequency in North Han Chinese |
| North_AN: | Total number of alleles in North Han Chinese |
| Central_AF: | Allele frequency in Central Han Chinese |
| Central_AN: | Total number of alleles in Central Han Chinese |
| South_AF: | Allele frequency in South Han Chinese |
| South_AN: | Total number of alleles in South Han Chinese |
| Lingnan_AF: | Allele frequency in Lingnan Han Chinese |
| Lingnan_AN: | Total number of alleles in Lingnan Han Chinese |
| DP: | Raw read depth |
| VQSLOD: | Variant Recalibration Score from GATK |
Citation
Please cite these papers when using WBBC "Sites and allele Frequencies" data for your publications.
1. Cong PK, Bai WY, Li JC, Yang MY, Khederzadeh S, Gai SR, Li N, Liu YH, Yu SH, Zhao WW, Liu JQ, Sun Y, Zhu XW, Zhao PP, Xia JW, Guan PL, Qian Y, Tao JG, Xu L, Tian G, Wang PY, Xie SY, Qiu MC, Liu KQ, Tang BS, Zheng HF. Genomic analyses of 10,376 individuals in the Westlake BioBank for Chinese (WBBC) pilot project. Nat Commun. 2022 May 26;13(1):2939. doi: 10.1038/s41467-022-30526-x. (PMID: 35618720).
2. Cong PK, Khederzadeh S, Yuan CD, Ma RJ, Zhang YY, Liu JQ, Yu SH, Xu L, Gao JH, Pan HX, Li JC, Xie SY, Liu KQ, Tang BS, Zheng HF. Identification of clinically actionable secondary genetic variants from whole-genome sequencing in a large-scale Chinese population. Clin Transl Med. 2022 May;12(5):e866. doi: 10.1002/ctm2.866. (PMID: 35538921).
3. Zhu XW, Liu KQ, Wang PY, Liu JQ, Chen JY, Xu XJ, Xu JJ, Qiu MC, Sun Y, Liu C, Bai WY, Zhao PP, Xia J, Gai SR, Guan PL, Qian Y, Cong PK, Xie SY, Zheng HF. Cohort profile: the Westlake BioBank for Chinese (WBBC) pilot project. BMJ Open. 2021 Jun 28;11(6):e045564. doi: 10.1136/bmjopen-2020-045564. (PMID: 34183340).